To undertake clinical functional genomics research in the critically ill and to develop related collaborative, laboratory based research projects with scientific colleagues.
To disseminate knowledge and promote understanding of functional genomics in the wider intensive care community.
To develop collaborations with colleagues outside the UK, with the particular objective of recruiting larger patient cohorts to achieve increased power and to allow replication.
We would like to encourage investigators in the field of Critical Care Medicine in the UK to apply to the GAinS management committee for access to the archive, for scientifically sound projects. Investigators should initially submit a short outline of their proposed research to the committee and may be invited to subsequently submit a more detailed plan of investigation.
Genomic Advances in Sepsis (GAinS)
Genetics of Sepsis & Septic shock (GenOSept)
Identifying regulatory DNA sequence variants in sepsis